When I evacuated from New Orleans for Katrina in '95, I was only able to take my backup clone and boot from that via a friend's PowerBook. At some point (after a couple weeks of starting up from the external and running it) InDesign wouldn't launch. I called Adobe and got them to reset the "allowable non-primary machine starts" and the guy told me he'd reset it to something ridiculously high so I wouldn't have to worry about it.
That was 2005, though, so the system has probably changed since then. Not directly helpful, but more like a cocktail party story I break in and share.
So, suffice to say, I was able to boot from the external and work for a good amount of time and, when it stopped working, a 15 minute (literally) phone call cleared up the issue.