Don't have to be in ranked order, but can be if you prefer
Mine:
Accidental Tech Podcast-wonderful tech stuff, mostly Apple, but lots of other stuff, too
Ones and Toole-really good, accessible political and economic analysis from one of the top academics
The Tim Ferris Show-mostly "improve your life", with an emphasis on business and health.
The Peter Attia Drive-amazing info on health, gets into the weeds on the nitty-gritty science sometimes
WTF with Marc Marron-celebrity interviews, with a lot of heart and irreverence
Runner-ups
Sway, with Kara Swisher-BUsiness interviews, some politics
Reconcilable Differences-Two very different guys talk about nearly everything.
The New Yorker, Politics and More-What it says on the label
The Jordan Harbinger Show-Interviews an amazing range of people-former Mafia hitmen, billionaires, cybersecurity experts, psychologist, you name it, with a ton of warmth
The Incomparable: Commentay on pop culture, often movies