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We’ll need more than one vaccine to beat the pandemic
Posted by: Sarcany
Date: November 15, 2020 05:52PM
Interesting insights.

[arstechnica.com]

We’ll need more than one vaccine to beat the pandemic

All COVID vaccine candidates work in different ways; none will be perfect for all.

Pfizer’s vaccine has to be stored and shipped at ultracold temperatures, less than 80 degrees below zero—it’ll keep for a few days at higher but still very cold conditions. And it needs vials made of a special glass that’s able to tolerate the freezing temperatures. (This is neat, actually—the key is that the glass is low in boron, exactly the opposite of famously temperature-change-tolerant Pyrex glass, which is a mix of boron and silicon dioxide. The glassmaker Corning has a $204 million contract with the government to make it and cut a deal in May to provide it to Pfizer. Whether Corning can make enough is the tricky part.)

All that shipping and freezing requires a level of technical sophistication that, for now at least, mostly exists in hospitals and labs—posing significant logistical challenges in rural areas and in the developing world...

Vaccine makers know how to compare different vaccines against the same disease in “noninferiority” studies. They already do that for influenza shots. COVID-19 vaccines might have entirely different “correlates of protection,” the thing that’s actually conferring immunity. Some might induce more neutralizing antibodies, the immune system’s general infantry, while others might induce more T cells, a more specifically targeted fighter...




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Re: We’ll need more than one vaccine to beat the pandemic
Posted by: Speedy
Date: November 15, 2020 05:55PM
I’m going to try them all.



Saint Cloud, Minnesota, where the weather is wonderful even when it isn't.
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Re: We’ll need more than one vaccine to beat the pandemic
Posted by: mattkime
Date: November 15, 2020 06:00PM
I'm glad that there are smart people who realize more than one approach is worthwhile.



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Re: We’ll need more than one vaccine to beat the pandemic
Posted by: cbelt3
Date: November 15, 2020 06:16PM
Quote
Speedy
I’m going to try them all.
You’ll evolve into Mach 10 Speedy .... immune to all Coronaviruses ..
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