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Mix-and-match vaccines...
Posted by: Sarcany
Date: October 13, 2021 10:27PM
[arstechnica.com]

Mixing and matching COVID-19 vaccines for booster doses appears safe and as effective—if not more effective—than sticking with the same vaccine for a booster dose. That's according to preliminary data posted online Wednesday from a clinical trial run by the National Institutes of Health.

The trial bolsters what some have long hoped: that mixing and matching vaccines could provide stronger, broader protection against the pandemic virus and all its variants.

The trial was not large enough to definitively indicate which combination of vaccines offers the best protection. And the early results, available on a preprint server, have not yet been peer-reviewed. But the preliminary trial findings do hint that Moderna's mRNA vaccine may offer the strongest protection all around—backing up similar findings from earlier vaccine-effectiveness studies. The data also suggests that people who received the one-shot Johnson & Johnson vaccine may want to get a boost with one of the two mRNA vaccines, either Moderna's or Pfizer/BioNTech's.


Yep.



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Re: Mix-and-match vaccines...
Posted by: PeterB
Date: October 14, 2021 10:31AM
Quote
Sarcany
[arstechnica.com]

Mixing and matching COVID-19 vaccines for booster doses appears safe and as effective—if not more effective—than sticking with the same vaccine for a booster dose. That's according to preliminary data posted online Wednesday from a clinical trial run by the National Institutes of Health.

The trial bolsters what some have long hoped: that mixing and matching vaccines could provide stronger, broader protection against the pandemic virus and all its variants.

The trial was not large enough to definitively indicate which combination of vaccines offers the best protection. And the early results, available on a preprint server, have not yet been peer-reviewed. But the preliminary trial findings do hint that Moderna's mRNA vaccine may offer the strongest protection all around—backing up similar findings from earlier vaccine-effectiveness studies. The data also suggests that people who received the one-shot Johnson & Johnson vaccine may want to get a boost with one of the two mRNA vaccines, either Moderna's or Pfizer/BioNTech's.


Yep.

Way ahead of the curve on this one... grinning smiley [forums.macresource.com]

... to me, it makes logical sense that mixing-and-matching is going to be beneficial, since you're increasing the antibody repertoire. I'd like to see more vaccines targeting the non-spike protein parts of the virus though:

[theconversation.com]
[www.theatlantic.com]




Freya says, 'Hello from NOLA, baby!' (Laissez bon temps rouler!)
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Re: Mix-and-match vaccines...
Posted by: mrbigstuff
Date: October 14, 2021 11:03AM
It does seem logical. Now to get the Novavax vaccine to market and have another vector.
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